Being overweight, obese, and morbidly obese rank among some of the top concerns for Americans. According to the National Institutes of Health: Office of Dietary Supplements, approximately 15 percent of adults in the US have used a weight-loss dietary supplement previously. Furthermore, women are more likely to use a weight-loss supplement than men, and Americans spend approximately $2 billion per year on oral weight-loss supplements. Many different supplements exist, and some studies have found evidence to suggest conjugated linoleic acid (CLA) may be able to help with weight-loss. Take a look at some of the top factors in choosing a weight-loss supplement and how CLA helps to drive weight loss.
Within the Office of Dietary Supplements’ page, CLA is described as promoting apoptosis in adipose tissue. Apoptosis is the effect of causing a cell to rupture from the excess intake of a given substance. In this case, apoptosis tends to occur as an adipose cell takes on too much material from the serum in the blood and surrounding tissues. In other words, the individual fat cells, if it could be described as that, slowly rupture and die.
In late 2015, several researchers sought to define how CLA may positively affect body composition and reduce cardio-metabolic risk factors. In the study, A Review On Effects of Conjugated Linoleic Acid on Body Composition and Energetic Metabolism, researchers identified potential side effects of CLA supplementation, such as hypoglycemia, deposition of fatty tissue within the liver, and insufficient levels in the lipid profile.
Since previous studies on the benefits of CLA for reducing body fat, researchers in this study sought to determine if the effects could be replicated on an experimental basis, as well as in practice. Moreover, researchers were able to prove CLA did impact body composition by reducing fat mass in experimental models and some participants. However, the overall findings could not suggest a definitive result for all participants. Yet, more evidence exists.
In 2006, a research team of dietitians, clinicians, and nursing staff studied the potential effects of conjugated linoleic acid in reducing body fat. In the study, the Role of Conjugated Linoleic Acid in Reducing Body Fat and Preventing Holiday Weight Gain, researchers studied a group of individuals between the ages of 18 and 44 for a period of six months.
One group in the study was given a placebo, while the other group was given a CLA supplement. The group who received the CLA supplement appeared to be better suited to response to insulin spikes, changes in the blood lipid composition, and function of the liver throughout the holiday season. Ultimately, researchers concluded CLA supplementation could help reduce body fat and help prevent weight gain during the season. Within this study, researchers did not identify any adverse effects of CLA supplementation. However, researchers were unable to scientifically ensure all participants avoided exercise and maintained a restricted diet. As a result, the potential results of the study could also be attributed to positive changes in a sedentary lifestyle and diet.
CLA has been extensively studied for its potential weight-loss properties. By understanding how CLA directly attacks adipose tissue, which is another name for fatty tissue, an individual can see how this supplement may be a solution to weight loss when other options have failed. Before starting any weight-loss regimen, please consult your physician, especially if you have any underlying medical conditions.