People may take statins for a variety of reasons. Statins refer to a class of medications commonly used to reduce cholesterol levels in otherwise healthy individuals, as well as those who may be predisposed to problems with the cardiovascular system. For those suffering from heart disease, COPD, coronary atherosclerotic disease (CAD), poor circulation, and diabetes, statin use may result in the depletion of CoQ10, explains the publication, Safety of Statins. This deficiency may be responsible for many different additional health ailments, albeit these side effects are often seen as minimal issues when compared to the potential health risks of high cholesterol levels. Take a look at what statins have to do CoQ10 and how a CoQ10 supplement may help.
Must statins have the word, “statin,” in the name of the drug. For example, pravastatin and simvastatin are two of the most common cholesterol medications. These medications help to reduce the level of low-density lipids, while increasing the level of high-density lipids in the blood. As a result, the potential risk of heart attack, stroke, and other problems with the cardiovascular system is reduced. However, the treatment of cholesterol with statins has a tendency to strip the body of CoQ10, as explained by the Healthline.
CoQ10 is required for the muscles to return to a relaxed, toned state after contraction, explains the publication, Statin-Associated Muscle Symptoms: Impact On Statin Therapy—European Atherosclerosis Society Consensus Panel Statement On Assessment Common Aetiology, And Management. Unfortunately, statins result in the premature disposal of CoQ10, or coenzyme Q10, which leaves the muscles in a overly-tense state. CoQ10 may help muscles retain tone, which means the muscle is not completely relaxed when not being used. In other words, the muscles resting state can be increased or decreased to account for changes and everyday activities.
When CoQ10 is not present, the muscle may be more subject to cramping, which reduces quality of life. In the study, Coenzyme Q10 and Statin-Induced Mitochondrial Dysfunction, researchers out to uncover how CoQ10 deficiency affects the function of energy-producing organelles, or mitochondria. Participants in the study were split into two groups. One group received a CoQ10 supplement and typical statin therapy. The other group continued statin therapy without the introduction of a CoQ10 supplement. The group who did not receive a CoQ10 supplement seemed to have a lower level of CoQ10 in the bloodstream. Furthermore, participants of this group had an increased rate of creatinine phosphokinase (CPK). These CPK levels are indicative of the death of cellular tissue in tissues with a highly-concentrated number of mitochondria per cell, such as cardiac and skeletal tissue. As a result, researchers assumed the use of CoQ10 may help restore CoQ10 levels to benefit cellular health when taking a statin.
Throughout history, researchers have sought to find medications to treat today's health problems, yet many of the potential side effects from medication can feel almost as bad as the original disease or disorder. Fortunately, researchers are starting to understand how alternative therapies, such as the introduction of a CoQ10 supplement to the diet, can help to reduce the potential side effects of these medications. For statins, the worse side effect has often been severe cramps and pain, and a CoQ10 supplement, such as those in Niveau™ products, may be a potential solution for reducing the side effects of taking cholesterol-lowering medications.